Semantic satiation is a cognitive neuroscience phenomenon in which repetition causes a word or phrase to temporarily lose meaning for the listener, who can only process the speech as repeated meaningless sounds. The explanation for the phenomenon was that verbal repetition repeatedly aroused a specific neural pattern in the cortex which corresponds to the meaning of the word. Rapid repetition causes both the peripheral sensorimotor activity and the central neural activation to fire repeatedly, which is known to cause reactive inhibition, hence a reduction in the intensity of the activity with each repetition.
Several activities demonstrate the operation of the semantic satiation effect in various cognitive tasks such as rating words and figures that are presented repeatedly in a short time, verbally repeating words then grouping them into concepts, adding numbers after repeating them out loud, and bilingual translations of words repeated in one of the two languages. In each case subjects would repeat a word or number for several seconds, then perform the cognitive task using that word. It was demonstrated that repeating a word prior to its use in a task made the task somewhat more difficult.
The Daily Omnivore 