Archive for July 21st, 2010

July 21, 2010


gene hunting

The International HapMap Project an organization that aims to develop a haplotype map (HapMap) of the human genome, which will describe the common patterns of human genetic variation. Haplotypes are contiguous strings of DNA. HapMap is a key resource for researchers to find genetic variants affecting health, disease, and responses to drugs and environmental factors. The information produced by the project is made freely available to researchers around the world.

Unlike with the rarer Mendelian diseases, combinations of different genes and the environment play a role in the development and progression of common diseases (such as diabetes, cancer, heart disease, stroke, depression, and asthma), or in the individual response to pharmacological agents. To find the genetic factors involved in these diseases, one could in principle obtain the complete genetic sequence of several individuals, some with the disease and some without, and then search for differences between the two sets of genomes. This approach is currently infeasible because of the cost of full genome sequencing. The HapMap project proposes a shortcut.

July 21, 2010

La Mexicaine De Perforation


La Mexicaine De Perforation is a subdivision of a French group called the L’UX (Urban eXperiment), which holds clandestine artistic events. In September 2004, french police discovered a fully functional underground movie theatre run by La Mexicaine De Perforation in the catacombs of Paris.

When the police returned for a formal investigation, all the equipment had disappeared—all that was left was a note on the floor reading, ‘Do not search’ (‘Ne cherchez pas’). The members of L’UX are largely secret, but its spokesman is Lazar Kunstmann who published La Culture En Clandestins L’UX relating 25 years of clandestine cultural actions.