Psychoactive toads are amphibians from which psychoactive substances from the family of bufotoxins can be derived. The skin and poison of Bufo alvarius (Colorado River toad or Sonoran Desert toad) contain 5-MeO-DMT and bufotenin, which both belong to the family of hallucinogenic tryptamines. The skin or poison of the toads may produce psychoactive effects when ingested. To obtain the psychoactive substances the toxin of psychoactive toads is commonly milked from their poison glands. The milking procedure does not harm the toad — it consists of stroking the animal under its chin to initiate the defensive poison response.
Once the liquid toxin has been collected and dried, it can be used for its psychedelic effects. The toad takes about a month to refill its poison glands. Rumors dating from the 1970s claimed that groups of hippies, some including teenagers, were licking the psychoactive toads to get high. Albert Most, founder of the Church of the Toad of Light and a proponent of recreational use of Bufo alvarius poison, published a booklet titled ‘Bufo alvarius: The Psychedelic Toad of the Sonoran Desert’ in 1983 which explained how to extract and smoke the secretions.
The Daily Omnivore 