Cannabidiol [kah-nuh-bi-dye-awl] (CBD) is a cannabinoid found in Cannabis. It is a major constituent of the plant, representing up to 40% in its extracts. It has displayed sedative effects in animal tests. Some research, however, indicates that CBD can increase alertness. It may decrease the rate of THC clearance from the body, perhaps by interfering with the metabolism of THC in the liver. Medically, it has been shown to relieve convulsion, inflammation, anxiety, and nausea, as well as inhibit cancer cell growth. Recent studies have shown cannabidiol to be as effective as atypical antipsychotics in treating schizophrenia.

A Cannabis Indica plant may have a CBD/THC ratio 4:-5 times that of Cannabis sativa. Marijuana with relatively high ratios of CBD:THC is less likely to induce anxiety than vice versa. This might partial be due to CBD’s antagonist effects at the cannabidanoid receptor, compared to THC’s partial agonist effect. The relatively large amount of CBD contained in Cannabis indica, means, compared to a sativa, the effects are modulated significantly. The effects of Sativa are well known for its cerebral high, hence used daytime as medical cannabis, while Indica are well known for its sedative effects and preferred night time as medical cannabis.


One Comment to “Cannabidiol”

  1. Also worth mentioning is the endogenous cannabinoid which these herbal neurotransmitters mimic: anandamide. Named after the Sanskrit word for “bliss” it says a lot about the joys of herb, and even occurs naturally in chocolate. Another toke? Yes please.

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